16 de fev de 2012

Neoplasmas envolvendo o sistema nervoso central de cães:26 casos (2003-2011)

Autores: Santos, RP, Fighera RA, Beckmann DC, Brum JS, Ripplinger A, Neto DP, Baumhardt R, Mazzanti A.

RESUMO


O objetivo deste estudo retrospectivo foi identificar cães com neoplasmas envolvendo o sistema nervoso central (SNC), atendidos entre janeiro de 2003 a junho de 2011, no HVU-UFSM, e obter informações a respeito da raça, do sexo, da idade, dos sinais neurológicos, da localização, da evolução clínica, do tipo e da origem do tumor e dos achados de exames complementares. Os 26 neoplasmas envolvendo o SNC incluídos nesse estudo ocorreram principalmente em Boxers (35%), com predomínio de idade de cinco anos ou mais (92,3%). A evolução dos sinais clínicos nos neoplasmas encefálicos variou entre sete e 115 dias e nos medulares entre sete a 420 dias. Os sinais neurológicos principais em cães com neoplasmas encefálicos e medulares foram alteração do nível de consciência (58%), caracterizada principalmente por sonolência, e hiperestesia espinhal (57%), respectivamente. As regiões tálamo-cortical e T3-L3 foram as mais acometidas (58% e 43%, respectivamente). Dos 12 neoplasmas que afetaram o encéfalo, 10 eram primários (83,3%). Dos 14 neoplasmas que afetaram a medula espinhal, apenas quatro eram primários (28,6%). Dos neoplasmas encefálicos e medulares primários, o mais comum foi o meningioma, perfazendo 40% e 75% dos casos, respectivamente.

ABSTRACT


This retrospective study was aimed to identify dogs with neoplasms affecting the central nervous system (CNS) and compile information on the affected breeds, sex, age group, anatomical site of the tumor, type of clinical signs and clinical course, and laboratory results. The study included the cases submitted to the Veterinary Teaching Hospital (HVU) of the Federal University of Santa Maria (UFSM), Brazil, from January 2003 to June 2011. The 26 neoplasms affecting the CNS included in this study occurred mainly in Boxers (35%) and the predominantly affected age-group was 5-year-old or older (92.3%). The course of clinical signs in dogs with brain neoplasms was 7-115 days and that of spinal cord tumors was 7-420 days. The most frequently observed neurological signs in dogs with brain and spinal cord neoplasms were respectively changes in the conscience levels (58%), which were characterized by somnolence, and spinal hyperesthesia (57%). The cortico-thalamic region and the T3-L3 spinal cord segment were the most frequently anatomical sites involved (58% and 43%, respectively). Ten out 12 neoplasms affecting the brain were primary (83.3%) whereas only four of those 14 neoplasms affecting the spinal cord were primary (28.6%). Meningioma was the most frequent m primary neoplasms affecting


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